[Phospholipase A2 activity in rat serum. Association of two proteins (author's transl)]

In the rat, blood coagulation is accompanied by activation of a plasma phospholipase A2 due to a factor contained in blood platelets and released in plasma by platelet lysis. This activity can be obtained in vitro by treating plasma devoid of platelets with a platelet lysate. The results reported in this communication show the activity of serum phospholipase to result from an association of two proteins, inactive when isolated, one originating from plasma, the other from platelets, which can be broken down by fractionation on a column of Blue Sepharose CL-6B.