Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.5K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.5K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.6K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

34
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
34
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

33
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
33

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative factors predicting outcomes in patients with suspected perihilar cholangiocarcinoma referred for curative resection- a single-center 10-year experience.

Langenbeck's archives of surgery·2024
Same author

EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2019
Same author

A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).

Annals of oncology : official journal of the European Society for Medical Oncology·2018
Same author

Clinical and molecular characterization of patients with cancer of unknown primary in the modern era.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

Oncologist use and perception of large panel next-generation tumor sequencing.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

The course of necrotizing arteritis: Imaging with real-time B-mode ultrasonography.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015

Related Experiment Video

Updated: May 5, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

23.9K

Cutaneous vasculitis complicating coeliac disease

S Meyers, S Dikman, H Spiera

    Gut
    |January 1, 1981
    PubMed
    Summary

    Chronic uncontrolled coeliac disease can lead to rare complications like cutaneous leucocytoclastic vasculitis and nephritis. A strict gluten-free diet resolved these serious conditions, highlighting the importance of celiac disease management.

    Area of Science:

    • Gastroenterology
    • Nephrology
    • Dermatology

    Background:

    • Coeliac disease is an autoimmune disorder triggered by gluten, primarily affecting the small intestine.
    • Uncontrolled coeliac disease can lead to various extra-intestinal manifestations and complications.
    • Cutaneous leucocytoclastic vasculitis is a rare condition characterized by inflammation of small blood vessels in the skin.

    Observation:

    • A 38-year-old female with chronic, uncontrolled coeliac disease presented with cutaneous leucocytoclastic vasculitis.
    • Renal biopsy revealed mesangial nephritis with haematuria and proteinuria.
    • No other cause for the vasculitis or nephritis was identified besides the coeliac disease.

    Findings:

    • Immune complex deposition, potentially triggered by antigens crossing the abnormal small bowel mucosa, is speculated as the cause of vasculitis and nephritis.

    More Related Videos

    Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
    11:28

    Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis

    Published on: March 25, 2016

    10.3K
    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
    06:35

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

    Published on: February 8, 2019

    6.8K

    Related Experiment Videos

    Last Updated: May 5, 2026

    Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
    10:27

    Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

    Published on: December 15, 2011

    23.9K
    Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
    11:28

    Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis

    Published on: March 25, 2016

    10.3K
    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
    06:35

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

    Published on: February 8, 2019

    6.8K
  • The patient's skin lesions resolved completely following adherence to a strict gluten-free diet.
  • This case suggests a direct link between coeliac disease and the development of systemic vasculitis and nephritis.

    • Implications:

    • Highlights the potential for severe systemic complications in inadequately managed coeliac disease.
    • Emphasizes the importance of vigilant monitoring and strict dietary adherence for patients with coeliac disease.
    • Suggests that managing coeliac disease may resolve associated autoimmune-mediated conditions like vasculitis and nephritis.