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Related Experiment Videos

Deep vein thrombosis after thoracotomy

F R Jackaman, B J Perry, H Siddons

    Thorax
    |December 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Heparin prophylaxis significantly reduced deep vein thrombosis (DVT) after thoracotomy from 51% to 28% without increasing blood loss. DVT was more common in the leg opposite the surgery.

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    Area of Science:

    • Medical research
    • Surgical outcomes
    • Thrombosis prevention

    Background:

    • Deep vein thrombosis (DVT) is a significant risk following lateral thoracotomy.
    • Assessing prophylactic methods for DVT is crucial in surgical patients.

    Purpose of the Study:

    • To evaluate the efficacy of perioperative heparin prophylaxis in preventing DVT after lateral thoracotomy.
    • To assess the utility of the 125I fibrinogen uptake test in monitoring DVT prophylaxis.

    Main Methods:

    • Prospective study involving 183 patients undergoing lateral thoracotomy.
    • Comparison of DVT incidence between a control group and a group receiving heparin prophylaxis.
    • Utilized the 125I fibrinogen uptake test for DVT assessment.

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    Main Results:

    • Incidence of DVT in untreated patients was 51%.
    • Heparin prophylaxis reduced DVT incidence to 28% (P < 0.005) without increasing postoperative blood loss.
    • Thrombosis was significantly more frequent in the leg contralateral to the thoracotomy (P < 0.005).

    Conclusions:

    • Perioperative heparin prophylaxis is effective in reducing DVT after lateral thoracotomy.
    • The 125I fibrinogen uptake test is valuable for evaluating prophylaxis but not for routine clinical use.