Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertension treated by salt restriction

T Morgan, W Adam, A Gillies

    Lancet (London, England)
    |February 4, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phase I study of KW-2478, a novel Hsp90 inhibitor, in patients with B-cell malignancies.

    British journal of cancer·2015
    Same author

    Inhibiting MEK in MAPK pathway-activated myeloma.

    Leukemia·2015
    Same author

    The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma.

    Leukemia·2015
    Same author

    The harms of low-dose aspirin prophylaxis are overstated.

    Annals of oncology : official journal of the European Society for Medical Oncology·2014
    Same author

    United Kingdom Myeloma Forum position statement on the use of consolidation and maintenance treatment in myeloma.

    International journal of laboratory hematology·2014
    Same author

    Targeted obstetric haemorrhage programme improves incoming resident confidence and knowledge.

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2013
    Same journal

    Convergence of metabolic risk in obesity and normal BMI: does risk disappear?

    Lancet (London, England)·2026
    Same journal

    Metabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studies.

    Lancet (London, England)·2026
    Same journal

    Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

    Lancet (London, England)·2026
    Same journal

    The US Ebola response and the future of global health leadership.

    Lancet (London, England)·2026
    Same journal

    Daniel Mason: a tale of change.

    Lancet (London, England)·2026
    Same journal

    The 2026 Wakley-Wu Lien Teh Prize Essay: why medicine, and why stay?

    Lancet (London, England)·2026
    See all related articles

    Dietary salt restriction effectively lowers diastolic blood pressure in hypertensive patients. This approach is comparable to medication and should be considered before drug therapy for hypertension management.

    Area of Science:

    • Cardiology
    • Nutrition Science
    • Public Health

    Background:

    • Hypertension is a widespread health issue, particularly in developed nations.
    • Excessive dietary salt intake is a significant contributing factor to hypertension.
    • Current treatments include antihypertensive drugs and lifestyle modifications.

    Purpose of the Study:

    • To evaluate the efficacy of moderate dietary salt restriction in lowering diastolic blood pressure.
    • To compare the effects of salt restriction with antihypertensive drugs and no treatment.
    • To assess the potential of salt reduction as a primary intervention for hypertension.

    Main Methods:

    • A two-year study involving 31 patients with diastolic blood pressure between 95-109 mm Hg.
    • Treatment group: moderate salt restriction.

    Related Experiment Videos

  • Comparison groups: untreated control and drug-treated patients.
  • Main Results:

    • Salt restriction reduced diastolic blood pressure by 7.3+/-1.6 mm Hg.
    • This reduction was comparable to that achieved with antihypertensive drugs.
    • The untreated group experienced a rise in diastolic blood pressure by 1.8+/-1.1 mm Hg.
    • Many patients struggled with strict adherence to salt restriction.

    Conclusions:

    • Dietary salt restriction is an effective method for reducing diastolic blood pressure.
    • Salt restriction offers a viable alternative to drug therapy, especially for individuals with diastolic blood pressure between 90-105 mm Hg.
    • Reducing population-wide salt intake could help manage the hypertension epidemic.