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Bronchial involvement by Hodgkin disease

A Guzzon, R Kenda, G Bonadonna

    Tumori
    |October 31, 1978
    PubMed
    Summary

    This study details two rare cases of Hodgkin disease, lymphocyte depletion type, affecting the bronchi. Diagnosis was confirmed using fiberbronchoscope examination, highlighting this uncommon presentation of the disease.

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    Area of Science:

    • Pulmonology
    • Oncology
    • Pathology

    Background:

    • Hodgkin disease, lymphocyte depletion type, is a rare malignancy.
    • Bronchial involvement in Hodgkin disease is exceptionally uncommon.

    Observation:

    • Two patients presented with Hodgkin disease, lymphocyte depletion type, involving the bronchial tree.
    • One case showed right upper lobar bronchus involvement; the other had left main bronchus involvement.

    Findings:

    • Fiberbronchoscope examination with cytologic brushing and biopsy enabled accurate diagnosis.
    • Literature review confirms the rarity, with only 20 previously reported cases of bronchial involvement.

    Implications:

    • Highlights the importance of considering rare presentations in differential diagnosis.
    • Emphasizes the diagnostic utility of bronchoscopy in identifying unusual Hodgkin disease manifestations.
    • Contributes to the understanding of the spectrum of Hodgkin disease, lymphocyte depletion type.

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