Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory brainstem potentials in chronic alcoholics

H Begleiter, B Porjesz, C L Chou

    Science (New York, N.Y.)
    |March 6, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state.

    Neuroimage. Reports·2026
    Same author

    Leveraging Pretrained Vision Transformers for classifying Alcohol Use Disorder using Raw Resting-State EEG.

    bioRxiv : the preprint server for biology·2026
    Same author

    Alcohol use disorder is associated with increases in frontocentral phase-amplitude coupling strength during resting state.

    bioRxiv : the preprint server for biology·2025
    Same author

    The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences.

    Translational psychiatry·2021
    Same author

    Genome-wide association study identifies a novel locus for cannabis dependence.

    Molecular psychiatry·2017
    Same author

    An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry.

    Molecular psychiatry·2017
    Same journal

    A native sulfur deposit in Gale crater, Mars.

    Science (New York, N.Y.)·2026
    Same journal

    Coordinated demise of harmful algal blooms.

    Science (New York, N.Y.)·2026
    Same journal

    Genetic effects put into context.

    Science (New York, N.Y.)·2026
    Same journal

    Bacteria share proteins to survive antibiotics.

    Science (New York, N.Y.)·2026
    Same journal

    Impacts shaped Earth's first continents.

    Science (New York, N.Y.)·2026
    Same journal

    Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

    Science (New York, N.Y.)·2026
    See all related articles

    Chronic alcohol abuse significantly delays auditory brainstem potentials in abstinent alcoholics. This suggests alcohol-induced demyelination may affect auditory pathways.

    Area of Science:

    • Neuroscience
    • Audiology
    • Toxicology

    Background:

    • Chronic alcohol abuse is a widespread issue with significant health consequences.
    • Alcohol's neurotoxic effects are well-documented, but specific impacts on auditory pathways require further elucidation.

    Purpose of the Study:

    • To investigate auditory brainstem potential (ABP) abnormalities in abstinent chronic alcoholics.
    • To determine if chronic alcohol consumption leads to measurable deficits in auditory pathway transmission.

    Main Methods:

    • Auditory brainstem potentials (ABPs) were recorded in a group of abstinent chronic alcoholics.
    • ABPs were also recorded in a matched group of control subjects without a history of chronic alcohol abuse.
    • Latencies of specific peaks (II, III, IV, V) and overall brainstem transmission time were analyzed and compared between groups.

    Related Experiment Videos

    Main Results:

    • Significant delays in the latencies of peaks II, III, IV, and V were observed in the alcoholic group compared to controls.
    • Brainstem transmission time was demonstrably longer in the chronic alcoholics.
    • These findings indicate objective alterations in auditory signal processing within the brainstem.

    Conclusions:

    • Chronic alcohol abuse is associated with significant auditory brainstem pathway deficits.
    • The observed delays suggest potential demyelination of auditory tracts as a consequence of long-term alcohol exposure.
    • ABPs serve as a valuable tool for assessing the neurotoxic effects of alcohol on the central nervous system.