[Electroencephalographic Investigations of 4-Aminopyridine (author's transl)]

Electroencephalographic investigations of 4-aminopyridine were carried out in the non-anesthetized, immobilized rat. Under the influence of this agent seizure-like activity appeared in the hippocampal and subsequently in the neocortical recordings. This effect was antagonized by pretreatment with diazepam. The discussion deals with the central cholinergic action of 4-aminopyridine.