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[Technic and indication for controlled ultrafiltration]

R Schmidt, R Herrera, M Holtz

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |August 15, 1980
    PubMed
    Summary
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    Infusing concentrated human plasma during ultrafiltration dialysis prevents hypotension by maintaining osmolality and vital substances. This method effectively manages hyperhydration, even in patients prone to low blood pressure.

    Area of Science:

    • Nephrology
    • Cardiovascular Physiology

    Context:

    • Dialysis patients, especially those with acute complications, risk hypotonic circulatory conditions during sequential ultrafiltration hemodialysis.
    • Massive dehydration can be achieved rapidly via isolated ultrafiltration without compromising patient well-being.

    Purpose:

    • To investigate a method for preventing hypotensive episodes during sequential ultrafiltration hemodialysis.
    • To explore the efficacy of infusing concentrated human plasma during ultrafiltration.

    Summary:

    • Isolated ultrafiltration allows rapid dehydration. Sequential ultrafiltration hemodialysis can lead to hypotension.
    • Infusion of fourfold concentrated human dry plasma during ultrafiltration prevents hypotension by maintaining osmolality and circulation-effective substances.
    • This treatment effectively removes hyperhydration in patients susceptible to hypotension.

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    Impact:

    • Provides a strategy to mitigate a common complication in dialysis patients undergoing sequential ultrafiltration.
    • Enhances patient safety and tolerance during fluid management in renal replacement therapy.
    • Offers a solution for managing hyperhydration in hemodialysis patients with hypotension risk.