Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The kidney and diuretics]

E Mampel, W Koall, V Luci

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |September 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Diuretics like xanthines have minimal diuretic effects. Thiazides are effective for chronic renal insufficiency up to a creatinine clearance of 25 ml/min/1.73 m2, while furosemide has limitations in severe kidney disease.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Influence of renal replacement therapy on outcome of patients with acute renal failure.

    Kidney international. Supplement·1999
    Same author

    [Paraneoplastic IgA nephritis as the initial symptom of bronchial carcinoma].

    Pneumologie (Stuttgart, Germany)·1996
    Same author

    Peritoneal leak and chronic pericardial effusion in a CAPD patient.

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1996
    Same author

    Evolution of renal replacement therapy in East Germany from 1989 to 1992.

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1994
    Same author

    [Thromboembolic risk factors in kidney transplantation: hemorheologic examination in secondary polycythemia].

    Folia haematologica (Leipzig, Germany : 1928)·1989
    Same author

    [Thromboembolism risk factors in kidney transplant patients with secondary erythrocytosis in relation to hemorheologic aspects].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·1988
    Same journal

    [Report on the Fifth International Congress on Blood Transfusion, Paris, 13 to 19 September 1954].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    Same journal

    [Blood coagulation; literature from 1952 to 1954. VI].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    Same journal

    [Blood coagulation; publications from 1952-1954. V].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    Same journal

    [Blood coagulation from 1952-1954. IV].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    Same journal

    [Report on the fourth congress of the European Gastroenterological Society in Paris, 27 June to 2 July 1954].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    Same journal

    [The islands of Langerhans in pancreatic carcinoma].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·2014
    See all related articles

    Area of Science:

    • Nephrology
    • Pharmacology

    Context:

    • Chronic renal insufficiency (CRI) management involves diuretics.
    • Understanding the efficacy limits of diuretics is crucial for patient care.

    Purpose:

    • To evaluate the diuretic efficacy of xanthines, thiazides, and furosemide in varying stages of kidney function.
    • To determine the limitations of conservative treatment for CRI.

    Summary:

    • Xanthines show slight diuretic effects, dependent on nephron count.
    • Thiazide diuretics are indicated for CRI until creatinine clearance drops below 25 ml/min/1.73 m2.
    • Furosemide, even in high doses (up to 500 mg/24h), shows limited efficacy in patients with severe CRI (serum creatinine 2-20 mg/100 ml), with urinary sodium concentration not exceeding 90 mval/l.

    Related Experiment Videos

    Impact:

    • Establishes the limited utility of certain diuretics in advanced chronic renal insufficiency.
    • Informs clinical decisions regarding diuretic selection and dosage in patients with impaired kidney function.
    • Highlights the need for alternative treatment strategies beyond conservative management for severe CRI.