[Anovulation syndrome in nulligravidae following intake of hormonal contraceptives (author's transl)]

Evaluated in this paper is clinical experience recorded from 70 young women, aged between 14 and 27 years, with post-pill syndrome. The aetiology of post-pill amenorrhoea was found to be closely related to lability of cycle prior to pill-taking. Nearly 60 per cent of all patients had used Non-Ovlon. 10 patients had used Sequenz-Ovosiston. The prognosis of iatrogenic normogonadotrophic ovarian insufficiency was found to depend on the basal oestrogen level, reaction of corpus endometrium, and serum prolactin. Pregnancy was successfully induced in 53 per cent of all patients who wanted to have a child. The aboration rate accounted for 7.4 per cent. Clinical examination of the newborns did not give any clue as to accumulation of congenital malformations. Roughly 40 per cent of all patients remained to be anovulatory, in spite of intensive treatment.