Unilateral subacute sclerosing panencephalitis complexes with contralateral myoclonus

Area of Science:

• Neurology
• Neurophysiology

Background:

• Subacute sclerosing panencephalitis (SSPE) is a rare, progressive neurological disorder.
• Characteristic electroencephalogram (EEG) complexes and periodic myoclonus are hallmark clinical features of SSPE.

Observation:

• Unilateral presentation of EEG abnormalities in SSPE is infrequently recognized.
• The occurrence of unilateral SSPE-related EEG complexes alongside contralateral myoclonus is exceptionally rare.

Findings:

• This case report details an unusual manifestation of SSPE.
• The patient exhibited unilateral SSPE EEG complexes and contralateral myoclonus, challenging typical presentations.

Implications:

• Recognizing unilateral SSPE manifestations is crucial for timely diagnosis.
• This case expands the understanding of SSPE's diverse clinical and electrophysiological presentations.