Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leukemia and prior malignant and hematologic diseases: a case-control study

A Linos, R A Kyle, W M O'Fallon

    American Journal of Epidemiology
    |March 1, 1981
    PubMed
    Summary

    This study found a potential link between prior skin cancer and chronic lymphocytic leukemia (CLL). Further research is needed due to borderline statistical significance in this leukemia risk factor analysis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Healthy diets positively associated with health-related quality of life in children and adolescents from low socioeconomic areas: Findings from the Greek Food Aid Program, DIATROFI.

    Nutrition (Burbank, Los Angeles County, Calif.)·2024
    Same author

    Perceptions of parents and children, participating in a school-based feeding programme in disadvantaged areas in Greece: a qualitative study.

    Child: care, health and development·2016
    Same author

    Pulmonary tuberculosis associated with anomalous common left pulmonary vein entering the left innominate vein.

    The Journal of thoracic surgery·2010
    Same author

    Data mining: a new technique in medical research.

    Hormones (Athens, Greece)·2006
    Same author

    The influence of dietary patterns on the development of thyroid cancer.

    European journal of cancer (Oxford, England : 1990)·2003
    Same author

    Taxonomic characterization of two rubber degrading bacteria belonging to the species Gordonia polyisoprenivorans and analysis of hyper variable regions of 16S rDNA sequences.

    FEMS microbiology letters·2001

    Area of Science:

    • Hematology
    • Oncology
    • Epidemiology

    Background:

    • Leukemia is a significant hematologic malignancy.
    • Understanding risk factors for different leukemia types is crucial for early detection and prevention.
    • Previous studies have explored associations between prior malignancies and leukemia, with varying results.

    Purpose of the Study:

    • To investigate the association between prior malignancies and hematologic diseases in patients with leukemia.
    • To determine if specific types of prior cancers or hematologic disorders increase leukemia risk.

    Main Methods:

    • Retrospective case-control study design.
    • Inclusion of 138 leukemia patients and 276 controls from Olmsted County, Minnesota (1955-1974).
    • Examination of medical records for prior malignancy and hematologic disease diagnoses.

    Related Experiment Videos

    Main Results:

    • No overall significant excess of malignancy was observed when all leukemia and malignancy types were combined.
    • A fivefold increased risk of prior skin cancer was identified in patients with chronic lymphocytic leukemia (CLL).
    • This finding for skin cancer and CLL reached borderline statistical significance due to small sample size.

    Conclusions:

    • The study suggests a potential association between a history of skin cancer and the development of chronic lymphocytic leukemia.
    • Further investigation with larger cohorts is warranted to confirm the borderline statistically significant finding.
    • The role of prior hematologic disorders in leukemia development requires additional exploration.