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Related Experiment Videos

GENFILES: a computerized medical genetics information network. I. An overview

W D Loughman, J A Mitchell, D C Mosher

    American Journal of Medical Genetics
    |January 1, 1980
    PubMed
    Summary

    GENFILES is a comprehensive information network for medical genetics research and administration. This system utilizes advanced database management for efficient data handling in clinical genetics.

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    Area of Science:

    • Medical Genetics
    • Bioinformatics
    • Health Informatics

    Background:

    • Clinical genetics services generate vast amounts of data requiring efficient management.
    • Existing systems may lack integration and advanced data-handling capabilities.
    • The need for a centralized, accessible information system in medical genetics is critical.

    Purpose of the Study:

    • To describe the design and implementation of GENFILES, a comprehensive computer information network for medical genetics.
    • To highlight the unique features and benefits of the GENFILES system for research, service, and administration.
    • To evaluate the suitability of GENFILES as a regional clinical genetics information system.

    Main Methods:

    • Development of four major databases covering cytogenetics, prenatal diagnosis, genetic counseling clinics, and human cell culture.

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  • Implementation of RAMIS, a commercial database management system.
  • Utilization of microprocessor computers as intelligent terminals for enhanced data handling.
  • Integration of all databases into a directly accessed, large timesharing computer system.

    • Main Results:

    • GENFILES provides a comprehensive network for medical genetics information.
    • The system integrates data from cytogenetics, prenatal diagnosis, clinics, and cell culture.
    • Unique features include RAMIS database management and microprocessor-based intelligent terminals.
    • The system is designed for ease of use and moderate cost.

    Conclusions:

    • GENFILES is a robust and user-friendly information system for medical genetics.
    • The system effectively serves research, service, and administrative needs.
    • GENFILES is well-suited for implementation as a regional clinical genetics information system.