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Primary amoebic meningoencephalitis

A R Cain, P F Wiley, B Brownell

    Archives of Disease in Childhood
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

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    Primary amoebic meningoencephalitis (PAM) is a rare and fatal brain infection. This report details the third UK case in an 11-year-old girl infected by Naegleria fowleri after swimming in a hot spring pool.

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Parasitology

    Background:

    • Primary amoebic meningoencephalitis (PAM) is a rare and devastating infection of the central nervous system.
    • The causative agent, Naegleria fowleri, is a free-living amoeba found in warm freshwater environments.
    • This report documents the third UK case of PAM, highlighting its continued presence and threat.

    Observation:

    • An 11-year-old girl presented with symptoms consistent with PAM.
    • The patient had a history of swimming in a pool supplied by hot spring water.
    • Naegleria fowleri was identified in the water source, confirming the likely route of infection.

    Findings:

    • The case represents the third documented instance of PAM in the United Kingdom.
    • The infection was linked to exposure to a recreational water source contaminated with Naegleria fowleri.

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  • The clinical course underscores the aggressive nature of this amoebic encephalitis.

    • Implications:

    • Early diagnosis and treatment are critical for any chance of survival in PAM cases.
    • Amphotericin B is suggested as a potential therapeutic agent, though its efficacy in PAM remains challenging.
    • Public health awareness regarding safe water practices in warm environments is crucial to prevent Naegleria fowleri infections.