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Radiation-induced parotid cancer
Archives of Surgery (Chicago, Ill. : 1960)
|March 1, 1981
Summary
Radiation exposure to the head or neck may increase the risk of developing parotid gland tumors. This study proposes criteria to identify radiation-induced parotid cancers.
Area of Science:
- Oncology
- Radiation Oncology
- Head and Neck Surgery
Background:
- Head and neck irradiation was historically used for various benign and malignant conditions.
- A potential link exists between prior radiation exposure and the development of parotid gland tumors.
Purpose of the Study:
- To investigate the association between past head and neck irradiation and the incidence of primary malignant parotid gland tumors.
- To establish criteria for identifying radiation-induced parotid gland tumors.
Main Methods:
- Retrospective analysis of 72 primary malignant parotid gland tumor cases treated between 1950-1978.
- Inclusion of 26 previously reported cases from other authors.
- Evaluation of patient age, sex, radiation exposure details, and latent periods.
Main Results:
- Six of 72 analyzed cases developed parotid tumors 2-24 years post-irradiation.
- Proposed criteria for radiation-induced parotid tumors include documented exposure, gland involvement, minimum 300 rads, and a 2-year latent period.
Conclusions:
- Past head and neck irradiation is a potential risk factor for developing parotid gland tumors.
- Surgeons should consider radiation history when evaluating parotid tumors due to the possibility of radiation induction.