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Normal human tear pH by direct measurement

M B Abelson, I J Udell, J H Weston

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |February 1, 1981
    PubMed
    Summary
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    This study determined normal tear pH in humans, finding a range of 6.5 to 7.6 with a mean of 7.0. This rapid measurement method enhances understanding of tear physiology and buffering capacity.

    Area of Science:

    • Ophthalmology
    • Physiological Measurement

    Background:

    • Tear film pH is crucial for ocular surface health and comfort.
    • Accurate measurement of tear pH is essential for understanding ocular surface homeostasis.

    Purpose of the Study:

    • To establish the normal pH range of human tear fluid.
    • To evaluate a novel method for rapid and accurate tear pH measurement.

    Main Methods:

    • Tear pH was measured in 44 healthy subjects.
    • A microcombination glass pH probe was immersed in the inferior cul-de-sac tear fluid.

    Main Results:

    • The normal tear pH range was determined to be 6.5 to 7.6.
    • The mean tear pH value was found to be 7.0.

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    Conclusions:

    • The microcombination glass pH probe offers a rapid and accurate method for assessing tear pH.
    • This technique can improve the understanding of tear physiology and buffering capacity.