Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Consanguinity among the Saudi Arabian population

M A el-Hazmi1, A R al-Swailem, A S Warsy

  • 1Department of Medical Biochemistry, King Khalid University Hospital, Riyadh, Saudi Arabia.

Journal of Medical Genetics
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relevance of <i>KISS1</i> gene polymorphisms in susceptibility to polycystic ovary syndrome and its associated endocrine and metabolic disturbances.

British journal of biomedical science·2020
Same author

Obesity and overweight in type II diabetes mellitus patients in Saudi Arabia.

Saudi medical journal·2016
Same author

Hepatitis A in Saudi Arabia: A comparative sero-epidemiological study.

Saudi medical journal·2016
Same author

Relationship between obesity, overweight and plasma lipids in Saudis.

Saudi medical journal·2016
Same author

Obesity and overweight in type II diabetes mellitus patients in Saudi Arabia.

Saudi medical journal·2016
Same author

Wireless shortwave: A new coagulation procedure.

Annals of Saudi medicine·2010
Same journal

Longest surviving patient with a homozygous splice-altering <i>EGFR</i> pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.

Journal of medical genetics·2026
Same journal

Functional characterisation and pathological significance of variants of <i>MEF2C</i> promoter in tetralogy of Fallot.

Journal of medical genetics·2026
Same journal

Identification of biallelic loss-of-function <i>PREP</i> variants in three individuals with syndromic intellectual disability.

Journal of medical genetics·2026
Same journal

Inherited retinal disease genes with dual inheritance patterns: insights from the IRD-PT registry.

Journal of medical genetics·2026
Same journal

Interpreting <i>TP53</i> variants: somatic mosaicism and <i>ERCC6L2</i>-driven clonal evolution.

Journal of medical genetics·2026
Same journal

Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome.

Journal of medical genetics·2026
See all related articles

Consanguineous marriages are highly prevalent in Saudi Arabia, affecting 57.7% of families studied. First cousin unions are the most common type, highlighting a significant trend in the region.

Area of Science:

  • Population Genetics
  • Human Genetics
  • Medical Genetics

Background:

  • Consanguineous marriages, unions between blood relatives, are culturally significant in many societies.
  • Understanding consanguinity prevalence is crucial for assessing potential genetic risks in populations.

Purpose of the Study:

  • To determine the prevalence of consanguineous marriages in Saudi Arabia.
  • To identify the types and patterns of consanguineous unions across different provinces.
  • To calculate the inbreeding coefficient (F) and discuss the implications of high consanguinity rates.

Main Methods:

  • A cross-sectional study involving interviews with 3212 Saudi families.
  • Data collection focused on the marital relationship between husband and wife.

Related Experiment Videos

  • Analysis of consanguinity rates and inbreeding coefficients by province and specific geographic areas.

    • Main Results:

    • The overall prevalence of consanguineous marriages in Saudi Arabia was 57.7%.
    • First cousin marriages were the most frequent (28.4%), followed by distant (15.2%) and second cousin (14.6%) marriages.
    • Consanguinity rates varied by province (52.1%–67.7%), with Samtah showing the highest rate (80.6%) and Abha the lowest (34%). The inbreeding coefficient (F) ranged from 0.020 to 0.030.

    Conclusions:

    • Saudi Arabia exhibits a high rate of consanguinity, comparable to countries with elevated levels.
    • Significant regional variations in consanguinity prevalence exist within Saudi Arabia.
    • The study underscores the need to address the potential genetic consequences associated with high rates of consanguineous marriages.