Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autonomic Nervous System: Overview

Autonomic Nervous System: Overview

The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...

Myasthenia Gravis: Diagnostic Tests

Myasthenia Gravis: Diagnostic Tests

Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...

Autonomic Nervous System

Autonomic Nervous System

The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control.
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...

Disorders of the Autonomic Nervous System

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...

Regulation of Heart Rates

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions.

Clinical and experimental dermatology·2021

Same author

Using Uniaxial Stress to Probe the Relationship between Competing Superconducting States in a Cuprate with Spin-stripe Order.

Physical review letters·2020

Same author

High-Temperature Charge-Stripe Correlations in La_{1.675}Eu_{0.2}Sr_{0.125}CuO_{4}.

Physical review letters·2020

Same author

Endpoint stiffness magnitude increases linearly with a stronger power grasp.

Scientific reports·2020

Same author

Increase in Grasp Force Reflects a Desire to Improve Movement Precision.

eNeuro·2019

Same author

Development and application of 2.5 GPa-25 T high-pressure high-field electron spin resonance system using a cryogen-free superconducting magnet.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2018

Same journal

[The Role of Laboratory Medicine in Hematopoietic Stem Cell Transplantation "Echocardiogram"].

Rinsho byori. The Japanese journal of clinical pathology·2019

Same journal

[The Significance of Pulmonary Function Testing Before and After Allogeneic Stem Cell Transplantation].

Rinsho byori. The Japanese journal of clinical pathology·2019

Same journal

[Blood Transfusion Inspection].

Rinsho byori. The Japanese journal of clinical pathology·2019

Same journal

[The Role of Clinical Laboratory Technicians at Bone Marrow Transplantation : Blood Test].

Rinsho byori. The Japanese journal of clinical pathology·2019

Same journal

[The Foundation of Allogeneic Hematopoietic Stem Cell Transplantation and the Role of Clinical Laboratory Tests in This Field].

Rinsho byori. The Japanese journal of clinical pathology·2019

Same journal

[How to Interpret Data from Routine Laboratory Tests].

Rinsho byori. The Japanese journal of clinical pathology·2019

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Quantitative Autonomic Testing

Quantitative Autonomic Testing

Published on: July 19, 2011

[Laboratory evaluation of autonomic function]

¹Department of Clinical Laboratory, Nagoya University Hospital.

Rinsho Byori. the Japanese Journal of Clinical Pathology

|September 1, 1995

Summary

This summary is machine-generated.

Autonomic nervous system dysfunction, specifically orthostatic hypotension, can be diagnosed using the head-up tilt test. This test helps identify lesions in the baroreflex arc by measuring plasma noradrenaline and vasopressin levels.

More Related Videos

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Published on: April 29, 2013

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Toddlers - Resting and Developmental Challenges

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Toddlers - Resting and Developmental Challenges

Published on: February 25, 2016

Related Experiment Videos

Last Updated: Jun 25, 2026

Quantitative Autonomic Testing

Quantitative Autonomic Testing

Published on: July 19, 2011

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Published on: April 29, 2013

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Toddlers - Resting and Developmental Challenges

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Toddlers - Resting and Developmental Challenges

Published on: February 25, 2016

Area of Science:

Neuroscience
Cardiovascular Physiology

Background:

The autonomic nervous system, comprising sympathetic and parasympathetic branches, regulates involuntary bodily functions.
Both systems utilize preganglionic and postganglionic neurons to transmit signals from the central nervous system to peripheral targets.

Observation:

Orthostatic hypotension, a significant circulatory issue in autonomic failure, occurs when standing causes blood pooling, reduced cardiac output, and a subsequent blood pressure drop.
The head-up tilt test is a standard method to assess hemodynamic responses to upright posture, with a systolic blood pressure fall exceeding 30 mmHg indicating abnormal function.

Findings:

The head-up tilt test can evaluate the location of lesions within the baroreflex arc.
Measuring plasma noradrenaline (NA) and vasopressin (AVP) responses during the tilt test aids in pinpointing the site of autonomic dysfunction.

Implications:

Understanding autonomic nervous system function is crucial for diagnosing and managing conditions like orthostatic hypotension.
The head-up tilt test, combined with neurochemical markers, provides valuable insights into the integrity of the baroreflex arc and autonomic control of circulation.