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[Tuberculous spondylitis after intravesical BCG instillation: a case report]
Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|September 1, 1995
Summary
Tuberculous spondylitis is a rare complication of intravesical bacillus Calmette-Guerin (BCG) therapy for bladder cancer. Early diagnosis and appropriate antituberculosis treatment are crucial for successful outcomes.
Area of Science:
- Urology
- Oncology
- Infectious Diseases
Background:
- Intravesical bacillus Calmette-Guerin (BCG) is a standard treatment for superficial bladder cancer.
- BCG instillation can lead to various side effects and complications.
Observation:
- A 71-year-old male developed symptoms including pain, urinary frequency, and fever after BCG instillation.
- Radiological imaging initially suggested metastatic transitional cell carcinoma.
- Pathological examination confirmed tuberculous spondylitis of the Th7 vertebra.
Findings:
- The patient was successfully treated with antituberculosis therapy (streptomycin, rifampicin, isoniazid) and spinal fusion.
- The patient achieved remission for both bladder cancer and tuberculous infection.
Implications:
- Tuberculous spondylitis should be considered in the differential diagnosis of spinal lesions following BCG instillation.
- Prompt diagnosis and antituberculosis treatment are essential for managing this rare complication.
- This case highlights the importance of vigilance for potential adverse events associated with BCG immunotherapy.