Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Substernal goiter

E Newman1, A R Shaha

  • 1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Journal of Surgical Oncology
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Substernal goiters, often causing respiratory issues, require surgical removal for effective management. Surgical treatment yields excellent results with minimal risks, providing full symptom relief for patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The utility of parathyroid autofluorescence as an adjunct in thyroid and parathyroid surgery 2023.

Head & neck·2023
Same author

Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk.

bioRxiv : the preprint server for biology·2023
Same author

Analyses of registry data of patients with anti-GBM and antineutrophil cytoplasmatic antibody-associated (ANCA) vasculitis treated with or without therapeutic apheresis.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2021
Same author

The role of radioactive iodine in the management of patients with differentiated thyroid cancer - An oncologic surgical perspective.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2020
Same author

Evaluation of health and quality of life in apheresis patients - data from the WAA register.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2019
Same author

The central compartment - Center of controversy, confusion, and concern in management of differentiated thyroid cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same journal

Institutional Learning Curve in Esophagectomy: Technical Standardization of Gastric Conduit Formation and Conduit-Related Outcomes in 187 Consecutive Patients.

Journal of surgical oncology·2026
Same journal

Evaluating the Accuracy of ChatGPT-4o in Addressing Complex Clinical Questions Based on NCCN Guidelines for Rectal Adenocarcinoma.

Journal of surgical oncology·2026
Same journal

Racial Differences in Breast Cancer Treatment and Information Access.

Journal of surgical oncology·2026
Same journal

Comparative Analysis of CEM and Breast MRI: A Retrospective Study.

Journal of surgical oncology·2026
Same journal

The Treatment Efficacy for Patients Undergoing Combined Transanal-Transabdominal Endoscopic Resection of Rectal Anastomosis Stenosis.

Journal of surgical oncology·2026
Same journal

"It Depends on the Situation": Variability in How Surgical Oncologists Elicit and Integrate Patient Values.

Journal of surgical oncology·2026
See all related articles

Area of Science:

  • Thoracic Surgery
  • Endocrinology
  • Surgical Oncology

Background:

  • Substernal goiters have challenged surgeons since 1749.
  • While incidence decreased in the US due to iodized salt, they remain common globally and can present as mediastinal tumors.
  • These masses are typically benign but 3-15% can be malignant, often causing respiratory symptoms due to compression.

Purpose of the Study:

  • To review the challenges and current management strategies for substernal goiters.
  • To emphasize the importance of surgical intervention and perioperative considerations.
  • To highlight the efficacy and safety of surgical treatment for these mediastinal masses.

Main Methods:

  • Review of historical and current literature on substernal goiter management.

Related Experiment Videos

  • Discussion of diagnostic modalities including imaging (X-ray, CT scan).
  • Emphasis on surgical approaches and perioperative airway assessment.
  • Main Results:

    • Surgical management is the definitive treatment, with medical therapy being largely unsuccessful.
    • Diagnostic evaluation typically involves chest X-ray and CT scans; needle biopsy is contraindicated.
    • Most substernal goiters are removed via a cervical incision, with sternotomy or thoracotomy used occasionally.

    Conclusions:

    • Surgical treatment of substernal goiters offers excellent outcomes with minimal morbidity and mortality.
    • Careful perioperative airway evaluation is crucial due to potential intubation difficulties.
    • Patients can expect complete symptom resolution following successful surgical intervention.