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Neuromuscular dysfunction following eccentric exercise

J M Saxton1, P M Clarkson, R James

  • 1Department of Exercise Science, University of Massachusetts, Amherst, USA.

Medicine and Science in Sports and Exercise
|August 1, 1995
PubMed
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Eccentric exercise causes muscle damage, leading to increased tremor and impaired proprioception. These effects significantly disrupt neuromuscular function for days following the exercise bout.

Area of Science:

  • Exercise Physiology
  • Neuromuscular Function
  • Sports Medicine

Background:

  • Exercise-induced muscle damage (EIMD) is a common outcome of strenuous physical activity.
  • Understanding the impact of EIMD on neuromuscular control is crucial for rehabilitation and performance.
  • Tremor and proprioception are key components of neuromuscular function potentially affected by muscle damage.

Purpose of the Study:

  • To investigate the effects of exercise-induced muscle damage on tremor and proprioception.
  • To assess the duration and extent of neuromuscular function impairment following eccentric exercise.

Main Methods:

  • Participants performed 50 maximal eccentric muscle actions targeting forearm flexors.
  • Neuromuscular function was assessed by monitoring forearm flexor tremor and proprioception (joint position and force perception).

Related Experiment Videos

  • Serum creatine kinase activity and muscle soreness were measured to confirm muscle damage.

    • Main Results:

    • Significant increases in serum creatine kinase and muscle soreness confirmed muscle damage.
    • Impaired joint range of motion and reduced maximum strength were observed post-exercise.
    • Increased tremor amplitude persisted for 48 hours, and proprioceptive deficits (joint position and force perception) were significant.

    Conclusions:

    • Eccentric exercise-induced muscle damage leads to increased tremor amplitude and impaired proprioception.
    • These changes indicate a significant disruption of neuromuscular function in the days following damage-inducing exercise.
    • Proprioceptive accuracy was reduced when using a contralateral limb as a reference, highlighting central nervous system involvement.