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Vitamin supplementation for 1 year improves mood

D Benton¹, J Haller, J Fordy

¹Department of Psychology, University College Swansea, UK.

Neuropsychobiology

|January 1, 1995

Summary

High-dose vitamin supplements improved mood in healthy adults. Both males and females reported feeling more agreeable, with females also experiencing enhanced composure and mental health after a year of supplementation.

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Area of Science:

Nutritional Neuroscience
Psychopharmacology
Human Health and Nutrition

Background:

The relationship between vitamin intake and psychological well-being is an area of ongoing research.
Understanding how nutrient status influences mood states can inform public health recommendations.
Previous studies have suggested potential links between specific vitamins and mental health outcomes.

Purpose of the Study:

To investigate the effects of high-dose vitamin supplementation on mood in young, healthy adults.
To determine if vitamin status changes correlate with self-reported mood improvements.
To explore potential sex-specific differences in response to vitamin supplementation.

Main Methods:

A double-blind, placebo-controlled study involving 129 healthy young adults.
Participants received either a high dose (10x recommended daily allowance) of 9 vitamins or a placebo for one year.
Mood assessments and blood vitamin status were measured throughout the study period.

Main Results:

Males taking high-dose vitamins reported feeling more 'agreeable' after 12 months compared to placebo.
Females demonstrated significant mood improvements, including feeling more 'agreeable', 'composed', and reporting better mental health.
Mood improvements correlated with increased blood levels of riboflavin and pyridoxine; baseline thiamin status in females was linked to poorer mood.

Conclusions:

High-dose supplementation of 9 vitamins can positively influence mood states in healthy young adults, particularly in females.
Improved mood is associated with enhanced status of specific B vitamins, including riboflavin, pyridoxine, and thiamin.
These findings suggest a role for adequate vitamin status in maintaining psychological well-being.

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