Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sleep patterns in cyclic and pseudopregnant rats

S Q Zhang1, M Kimura, S Inoué

  • 1Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Japan.

Neuroscience Letters
|June 30, 1995
PubMed
Summary

Female rats exhibit distinct sleep pattern changes during reproductive cycles. Sleep reduction occurs during proestrus, while pseudopregnancy increases sleep, highlighting the sleep-reproduction link.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heparin inhibits the progression phase of subcultured endothelial cell proliferation in rat aorta.

Japanese journal of pharmacology·1992
Same author

Antiproliferative effects of the traditional Chinese medicine shimotsu-to, its component cnidium rhizome and derived compounds on primary cultures of mouse aorta smooth muscle cells.

Japanese journal of pharmacology·1992
Same author

[Quenching of ethidium-DNA fluorescence by novel acridines with antitumor activities].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·1992
Same author

Comparative study of penetration of lomefloxacin and ceftriaxone into transudative and exudative pleural effusion.

Antimicrobial agents and chemotherapy·1992
Same author

Analysis of the human tyrosine hydroxylase promoter-chloramphenicol acetyltransferase chimeric gene expression in transgenic mice.

Brain research. Molecular brain research·1992
Same author

Clotrimazole-induced modulation of hepatic cytochrome P450 enzymes in Syrian and Chinese hamsters.

Biochemical pharmacology·1992

Area of Science:

  • Neuroscience
  • Reproductive Biology
  • Sleep Science

Background:

  • The intricate relationship between sleep and reproductive functions remains incompletely understood.
  • Reproductive states, such as estrous cycles and pseudopregnancy, involve significant hormonal fluctuations that may influence sleep architecture.

Purpose of the Study:

  • To investigate the dynamic changes in sleep patterns in female rats across different reproductive phases.
  • To correlate observed sleep alterations with specific reproductive states like the estrous cycle and pseudopregnancy.

Main Methods:

  • Continuous monitoring of sleep-wakefulness states in female rats over a 4-week period.
  • Observation included two consecutive 4-day estrous cycles, a 12-day pseudopregnant period, and a subsequent 4-day cycle.
  • Analysis of nocturnal and diurnal sleep patterns, including non-rapid-eye-movement sleep (NREMS) and rapid-eye-movement sleep (REMS).

Main Results:

  • Proestrus was associated with a significant reduction in nocturnal NREMS and REMS.
  • Pseudopregnancy induced a notable increase in nocturnal NREMS and REMS, with NREMS elevated throughout and REMS during the early to mid-pseudopregnant period.
  • Diurnal REMS showed a tendency to decrease towards the end of pseudopregnancy.
  • Circadian rhythms of brain temperature remained unaffected by reproductive status.

Conclusions:

  • Sleep patterns exhibit significant, dynamic changes correlating with reproductive activities in female rats.
  • These sleep alterations during the estrous cycle and pseudopregnancy likely reflect underlying neuroendocrine adjustments.
  • Further research can elucidate the precise mechanisms linking sleep regulation and reproductive neuroendocrinology.

Related Experiment Videos