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[Pulmonary function in patients with rheumatic mitral valve disease. Preoperative evaluation]
M Strzyzakowska1, T Hryniewiecki, P Gutkowski
1I Kliniki Wad Serca.
Polskie Archiwum Medycyny Wewnetrznej
|January 1, 1995
Summary
Patients with mitral valve disease often show bronchial hyperresponsiveness and reversible airway obstruction. These lung function changes were not directly correlated with the severity of their heart condition.
Area of Science:
- Cardiology
- Pulmonology
- Medical Sciences
Background:
- Rheumatic mitral valve disease can affect multiple organ systems.
- Cardiac and pulmonary functions are closely interrelated.
- Understanding cardiac-airway interactions is crucial for managing complex cardiovascular conditions.
Purpose of the Study:
- To investigate the cardiac-airway interaction mechanism in patients with rheumatic mitral valve disease.
- To assess the prevalence of bronchial hyperresponsiveness and reversible airway obstruction in this patient group.
Main Methods:
- Studied 70 patients (61 combined mitral disease, 9 isolated mitral stenosis) across NYHA functional classes II-IV.
- Utilized noninvasive cardiological assessments including echocardiography and fluoroscopy.
- Performed comprehensive lung function studies: spirography, plethysmography, flow-volume curves, and histamine provocation tests.
Main Results:
- Bronchial hyperreactivity to histamine was observed in 75% of tested patients (mean PC40 = 0.1474 mg/ml).
- Reversible airway obstruction after FNT administration was noted in 61% of patients.
- No significant correlation was found between pulmonary function parameters and the cardiological status.
Conclusions:
- Patients with mitral valve disease exhibit significant bronchial hyperresponsiveness and reversible airway obstruction.
- These pulmonary findings appear independent of the cardiological status in mitral valve disease patients.
- Highlights a potential link between valvular heart disease and airway abnormalities.