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[Neurocysticercosis]

G Roos1, T Henze, F Gullotta

  • 1Pathologisches Institut, Städtisches Krankenhaus, Singen.

Der Pathologe
|September 1, 1995
PubMed
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Neurocysticercosis, a parasitic brain infection, caused a shunt-dependent hydrocephalus in a patient. Autopsy revealed parasitic cysts and leptomeningitis, highlighting the disease's severe neurological impact.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Parasitology

Background:

  • A 54-year-old female with a 10-year history of ventriculoperitoneal shunt for communicating hydrocephalus.
  • Previous transient gait disturbances and cerebral infarction at age 46 provided no definitive diagnosis.

Observation:

  • Development of a distinct organic brain syndrome after years of occasional disturbances.
  • Tentative diagnosis of neurocysticercosis based on patient history, cerebrospinal fluid analysis, and CT-detected cerebral microcalcifications.

Findings:

  • Autopsy revealed cicatricial residues of basal leptomeningitis with collapsed parasitic cysts.
  • Residual ependymitis led to aqueductal stenosis.
  • Death resulted from cachexia, bronchopneumonia, and a lung abscess.

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Implications:

  • This case highlights the severe neurological sequelae and potential lethality of neurocysticercosis.
  • While rare in some regions, neurocysticercosis remains a globally significant parasitic central nervous system disease.
  • The study underscores the importance of considering parasitic infections in unexplained neurological syndromes.