Related Experiment Videos
[Skin manifestations related to hepatitis C viruses]
M S Doutre1, C Beylot, M Beylot-Barry
1Service de dermatologie, hôpital du Haut-Lévêque, Pessac, France.
Insights
Hepatitis C virus (HCV) is linked to various skin conditions, including essential mixed cryoglobulinemia and porphyria cutanea tarda. Further research is needed to confirm its association with lichen planus and other dermatological issues.
Area of Science:
- Hepatology
- Dermatology
- Virology
Context:
- Hepatitis C virus (HCV) infection is a significant global health concern.
- HCV is known to cause liver disease (hepatitis) and affect other organs (extrahepatic manifestations).
- Dermatological conditions are increasingly recognized as extrahepatic manifestations of HCV.
Purpose:
- To review the association between Hepatitis C virus infection and various dermatological disorders.
- To highlight established links and areas requiring further investigation.
Summary:
- HCV infection is strongly associated with essential mixed cryoglobulinemia and porphyria cutanea tarda.
- The prevalence of HCV in other vasculitides like polyarteritis nodosa appears low.
- Lichen planus and other cutaneous conditions such as urticaria and erythema multiforme are occasionally observed in HCV patients.
Impact:
- Understanding these associations can improve diagnosis and management of HCV patients with skin conditions.
- Highlights the multisystemic nature of Hepatitis C virus infection.
- Emphasizes the need for dermatological screening in HCV patients and vice versa.
Abstract:
The hepatitis C virus causes both hepatic and extrahepatic disorders, particularly as regards dermatology. The link between essential mixed cryoglobulinemias and the C virus infection has been clearly evidenced., whereas its frequency seems low in other systemic vasculitis such as polyarteritis nodosa. Similarly, the link between C virus hepatopathy and porphyria cutanea tarda is now proven. Lichen planus is also described as being associated with this virus, but further epidemiological studies are required to determine the exact prevalence of lichen in C virus hepatopathy cases. Finally, various cutaneous disorders, such as urticaria, erythema multiforme, dermo-hypodermitis, etc, occasionally arise during acute or chronic hepatitis C.