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Updated: Aug 18, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
[Experience in using hydrotherapy in children with acute lymphoblastic leukemia at a sanatorium]
Insights
Adjuvant balneotherapy improved heart rate and circulation symmetry in children with acute lymphoblastic leukemia in remission. This rehabilitation method was safe and showed no adverse effects.
Area of Science:
- Pediatric Oncology
- Rehabilitation Medicine
- Cardiovascular Physiology
Context:
- Children (10-15 years) in long-term remission of acute lymphoblastic leukemia (ALL) often have concomitant diseases requiring rehabilitation.
- Assessing the efficacy and safety of complementary therapies in pediatric cancer survivors is crucial.
Purpose:
- To evaluate the impact of adjuvant balneotherapy on cardiovascular parameters in children with ALL in remission.
- To determine the safety profile of balneotherapy in this specific pediatric population.
Summary:
- Thirty-four children aged 10-15 years with ALL in remission received combined rehabilitation including adjuvant balneotherapy.
- Significant improvements were observed in heart rate regulation and a decrease in circulatory asymmetry.
- No side effects were reported during the balneotherapy intervention.
Impact:
- Balneotherapy can be a beneficial and safe adjunctive therapy for improving cardiovascular function in pediatric ALL survivors.
- Findings support the integration of balneotherapy into comprehensive rehabilitation programs for long-term cancer care.
- This study highlights a non-pharmacological approach to managing sequelae in childhood cancer survivors.
Abstract:
34 children aged 10-15 years in long-term remission of acute lymphoblastic leukemia were on combined rehabilitation for concomitant diseases. Adjuvant balneotherapy promoted improvement in the heart rate and decreased asymmetry of circulation. No side effects were registered.
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