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[Brain stem auditory evoked potentials in obstructive sleep apnea syndrome]

A Cimino1, R Speciale, S Gallina

  • 1Clinica Otorinolaringoiatrica Base, Università di Palermo.

Acta Otorhinolaryngologica Italica : Organo Ufficiale Della Societa Italiana Di Otorinolaringologia E Chirurgia Cervico-Facciale
|April 1, 1995
PubMed
Summary

Brainstem auditory evoked potentials (BAEP) show minor, inconsistent changes in obstructive sleep apnea syndrome (OSAS) patients. These BAEP alterations may stem from chronic hypoxia and hypercapnia associated with sleep apnea.

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Area of Science:

  • Neurophysiology
  • Sleep Medicine
  • Otolaryngology

Background:

  • Obstructive sleep apnea syndrome (OSAS) is a prevalent condition affecting respiratory function during sleep.
  • The potential involvement of the brainstem in OSAS pathogenesis remains an area of investigation.
  • Brainstem auditory evoked potentials (BAEP) offer a method to assess brainstem auditory pathway function.

Purpose of the Study:

  • To investigate the role of the brainstem in the pathogenesis of obstructive sleep apnea syndrome.
  • To evaluate brainstem auditory evoked potentials (BAEP) in patients diagnosed with moderate to severe OSAS.

Main Methods:

  • A study was conducted on 15 patients with moderate to severe OSAS and upper respiratory tract pathologies.
  • A control group of 15 healthy subjects was included for comparison.

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  • All participants underwent comprehensive audiometry, including BAEP testing with click trains at 11 and 51 Hz.

    • Main Results:

    • Morphological alterations and prolonged central conduction time (I-V interval) in BAEP were observed in only four OSAS patients.
    • The observed BAEP alterations were neither constant nor specific to the OSAS group.
    • Audiometry, tympanometry, and acoustic reflex tests were also performed.

    Conclusions:

    • The study found no consistent or specific BAEP abnormalities in OSAS patients.
    • The minor BAEP alterations noted may be secondary to the chronic hypoxic-hypercapnic conditions associated with OSAS.
    • Further research is needed to fully elucidate the brainstem's role in OSAS.