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Related Experiment Videos

Does ischemia occur with panic attacks?

D W Lint1, C B Taylor, L Fried-Behar

  • 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305-5542, USA.

The American Journal of Psychiatry
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

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Ambulatory electrocardiogram (ECG) monitoring during panic attacks in women with panic disorder revealed no ischemic events. Tachycardiac events occurred, but panic attacks were more symptomatic.

Area of Science:

  • Cardiology
  • Psychiatry
  • Clinical Medicine

Background:

  • Panic disorder is often associated with chest pain, mimicking cardiac ischemia.
  • Ambulatory electrocardiogram (ECG) monitoring is a tool to assess cardiac events during daily activities.

Purpose of the Study:

  • To investigate ambulatory ECG changes during panic attacks in patients diagnosed with panic disorder.
  • To determine if ischemic events occur concurrently with panic attacks in these patients.

Main Methods:

  • Ten women with panic disorder and chest pain during panic attacks were enrolled.
  • Participants underwent a symptom-limited exercise test and wore an ambulatory ECG monitor for up to 6 days.
  • A hand-held computer was used for symptom and event logging.

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Main Results:

  • Eight participants experienced panic attacks while monitored.
  • No ischemic events were detected during exercise tests or ambulatory monitoring.
  • Tachycardiac events occurred during panic attacks (12) and independently (84), with panic attacks being more symptomatic.

Conclusions:

  • Ambulatory ischemic changes were not observed during panic attacks in this cohort of women with panic disorder.
  • The findings suggest that chest pain during panic attacks in this population may not be attributable to myocardial ischemia.
  • Further research is warranted to understand the mechanisms of chest pain in panic disorder.