[Role of hepatocellular insufficiency and kidney failure on nutritional management]

Chronic liver disease as well as chronic renal failure are responsible for abnormal nutrient metabolism and high rates of undernutrition. Although surgery is frequently required in such patients, the perioperative nutritional management has not yet been extensively studied in these conditions. During chronic liver disease, preoperative nutritional status and postoperative outcome are correlated. However, nutritional status can only be considered as one out of several factors of the prognosis, including the grade of liver insufficiency and the type of surgical procedure. Thus, it is difficult to evaluate the real influence of undernutrition on postoperative outcome. Similarly, the usefulness of preoperative nutrition is not definitely demonstrated in this condition. The nutritional requirements of patients with liver cirrhosis are estimated to be protein 1g and 30-35 kcal.kg-1.d-1. The duration of nutritional supplementation before surgery may not exceed 10 days. Postoperative parenteral nutrition seems to be well tolerated during chronic liver disease. Although some data in the literature suggest that it may be of interest after liver transplantation, the efficacy of postoperative parenteral nutrition needs to be proven in larger series. In chronically uraemic patients, the effects of undernutrition on postoperative morbidity and mortality have been poorly studied. Infectious complications after renal transplantation are favoured by several factors, including immunosuppressive therapy and malnutrition. The efficacy as well as the tolerance of perioperative nutritional support in patients with chronic renal failure are poorly known. In haemodialysis patients, candidates for renal graft, the nutritional status is usually well preserved when the recommended nutritional needs are provided: proteins 1.2-1.4 g and 35-40 kcal.kg-1.d-1.