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Updated: Aug 12, 2026
13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
[Prognostic factors of prostatic cancer]
1Dept. of Urology, Faculty of Medicine Kyoto University.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 1, 1995
Summary
Prostate cancer detection has improved, but identifying prognostic factors is crucial for optimal treatment. Tumor characteristics and early response to therapy aid in predicting outcomes for localized and advanced prostate cancer.
Area of Science:
- Urology
- Oncology
- Pathology
Context:
- Significant advancements in prostate cancer diagnosis and treatment over the last decade.
- Improved detection rates attributed to systematic prostate biopsy and prostate-specific antigen (PSA) testing.
- Growing need for accurate prognostic indicators to guide treatment decisions for localized and advanced prostate cancer.
Purpose:
- To review current prognostic parameters for prostate cancer.
- To identify key indicators for localized and advanced disease.
- To highlight the potential of molecular biology in refining prognostic accuracy.
Summary:
- Tumor volume, lymph node status, and Gleason score are significant prognostic indicators for localized prostate cancer.
- For advanced prostate cancer, initial endocrine therapy response and primary tumor histopathology are important prognostic factors.
- Molecular biological approaches are emerging to provide novel prognostic parameters for improved treatment decision-making.
Impact:
- Enhanced ability to personalize treatment strategies for prostate cancer patients.
- Potential for earlier and more accurate prediction of treatment response and patient outcomes.
- Facilitates the integration of molecular data into clinical practice for better prostate cancer management.
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