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Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
Published on: November 1, 2011
Rift Valley fever epizootic in small ruminants in southern Mauritania (October 1993): risk of extensive outbreaks
H G Zeller1, A J Akakpo, M M Ba
1Institut Pasteur, Antananarivo, Madagascar.
Abstract:
Following the 1987 Rift Valley fever (RVF) epizootic/epidemic in southern Mauritania, RVF antibody prevalence in small ruminants decreased significantly from 1988 to 1992. In October 1993, at the end of the rainy season, an active RVF virus transmission was detected in several locations of southern Mauritania in small ruminants, in association with an increase of abortions. RVF IgM and IgG antibodies were recorded respectively in 65/390 (16.67%) and 73/390 (18.72%) animals. RVF IgM antibody prevalence was significantly higher in the > or = 2 years old group (26.02%) than in the 0.5- < 2 year old group (7.20%) (p = 0.01). The enzootic maintenance of RVF virus is discussed, as well as the risks of extension by traditional nomadic movements of herds.
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