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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

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[4-year mortality of heart failure with intact systolic function: a retrospective studies]

A Koegler1, G Roul, P Bareiss

  • 1Service de cardiologie, CHRU de Strasbourg, hôpital de Hautepierre, Strasbourg.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|July 1, 1995
PubMed

Insights

Patients with congestive heart failure and normal systolic function have a better cardiovascular mortality outlook. Age over 60 and high diastolic blood pressure increased risk in this group.

Area of Science:

  • Cardiology
  • Heart Failure Research

Background:

  • 30-40% of patients with congestive heart failure exhibit normal systolic function.
  • Distinguishing prognosis between heart failure types is crucial for patient management.

Purpose of the Study:

  • To compare 4-year global and cardiovascular mortality in patients with congestive heart failure and normal versus poor left ventricular systolic function.
  • To identify predictors of cardiovascular mortality in these patient groups.

Main Methods:

  • Retrospective study of 149 patients with congestive heart failure.
  • Group I: Poor left ventricular systolic function (EF = 26 +/- 9%).
  • Group II: Normal left ventricular systolic function (EF = 58 +/- 8%).
  • 4-year follow-up for global and cardiovascular mortality.

Main Results:

  • 4-year cardiovascular mortality was significantly lower in the normal systolic function group (21.6% vs 49%, p < 0.004).
  • Global mortality was comparable between the two groups.
  • Age > 60 years and diastolic blood pressure > 90 mmHg were associated with higher cardiovascular mortality, particularly in the normal systolic function group.

Conclusions:

  • Patients with congestive heart failure and normal systolic function have a better cardiovascular mortality prognosis compared to those with poor systolic function.
  • Age and diastolic blood pressure are important risk factors for cardiovascular mortality in patients with normal systolic function heart failure.

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