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Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay
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Published on: March 2, 2011

Changes in the ultrastructure and functions of immunocompetent cells under the influence of external heating,

P P Murzenok1, N I Netukova

  • 1Department of Applied Physiology, Institute of Physiology of Academy of Sciences, Minsk, Republic of Belarus.

Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1994
PubMed

The structural and functional organization of the rabbit immunocompetent cells after injection of human recombinant interleukin 1 beta (IL-1 beta), partially purified leukocytic pyrogen (LP), or after external heating (36 degrees C, 1.5 h) was compared. A rectal temperature increase being the same, there were similar and transient changes in epithelial and endothelial cells and macrophages, a rise in the proliferative activity of thymocytes and synthesis of IL-1-like activity, and a decrease in the interleukin 2 (IL-2) production by cultured splenic cells.

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