Synovial sarcoma of the heart. Correlation with cytogenetic findings

A primary sarcoma of the heart was submitted to cytogenetic studies, which showed a translocation t(X;18)(p11;q11.2). The translocation between X and 18 is a characteristic one in synovial sarcoma of the lower extremities. As the histological appearance was not helpful for further classification of this primary sarcoma, karyotypic analysis proved useful in confirming diagnosis of synovial sarcoma, which, to our knowledge, is an uncommon neoplasm in the heart.