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Selective transmission of hepatitis C virus in vivo and in vitro
M Hijikata1, K Mizuno, T Rikihisa
1Department of Bacteriology, Faculty of Medicine, University of Tokyo, Japan.
Archives of Virology
|January 1, 1995
Abstract:
A human plasma containing quasi-species of hepatitis C virus (HCV) was inoculated to a chimpanzee and to human lymphocytic cell lines, HPB-Ma clone 10-2, AD HPB, and Daudi, which support replication of HCV. Among six different hypervariable region (HVR) sequences detected in the inoculum, the same two were recovered both in vivo and in vitro.