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Related Experiment Videos

Systemic lupus erythematosus serositis

V H Low1, P D Robins, D J Sweeney

  • 1Department of Radiology, Sir Charles Gairdner Hospital, Nedlands, Australia.

Australasian Radiology
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

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Systemic lupus erythematosus (SLE) can present with gastrointestinal issues like bowel obstruction. Diagnosis relies on elevated autoantibodies, not just imaging or biopsy findings.

Area of Science:

  • Gastroenterology
  • Rheumatology
  • Radiology

Background:

  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
  • Serositis, inflammation of serous membranes, can be an initial presentation of SLE.
  • Gastrointestinal involvement in SLE, though less common, can mimic other abdominal pathologies.

Observation:

  • A case of SLE initially presenting as serositis is described.
  • Barium small bowel studies revealed spiculation, tethering, angulation, and obstruction.
  • Computed tomography (CT) demonstrated ascites and asymmetrical small bowel wall thickening.

Findings:

  • Laparotomy identified extensive patchy serosal and peritoneal plaques.
  • Biopsies of these plaques were inconclusive for a definitive diagnosis.

Related Experiment Videos

  • Diagnosis was confirmed by significantly elevated antinuclear antibodies (ANA) and anti-double stranded DNA (anti-dsDNA) antibodies.

    • Implications:

    • Highlights the varied imaging findings of SLE in the gastrointestinal tract.
    • Emphasizes the importance of serological markers in diagnosing SLE when imaging and biopsy are equivocal.
    • Suggests considering SLE in patients with unexplained gastrointestinal symptoms and serositis.