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Changes in survival patterns of very low-birth-weight infants from 1980 to 1993

J Roth1, M B Resnick, M Ariet

  • 1Department of Pediatrics, University of Florida, USA.

Archives of Pediatrics & Adolescent Medicine
|December 1, 1995
PubMed

Insights

Survival rates for very low-birth-weight infants improved significantly between 1980 and 1993, especially for black males and white females. Factors like race, sex, and transport status impact survival, guiding neonatal intensive care for premature infants.

Area of Science:

  • Neonatalogy
  • Perinatal Medicine
  • Public Health

Background:

  • Infant mortality remains a significant concern, particularly for very low-birth-weight (VLBW) infants.
  • Understanding survival patterns in VLBW infants is crucial for improving neonatal outcomes.

Purpose of the Study:

  • To analyze changes in survival rates for very low-birth-weight infants (<1500 g) from 1980 to 1993.
  • To identify demographic and clinical factors influencing survival in this vulnerable population.

Main Methods:

  • Analysis of 12,960 VLBW infant records from nine Florida perinatal intensive care centers.
  • Log linear regression used to generate survival curves based on birth weight, race, sex, and transport status.

Main Results:

  • Significant correlations found between race, sex, transport status, and infant survival.
  • Survival rates increased notably for transported black male infants and inborn white female infants.
  • By 1985, 95% survival was observed for neonates weighing 1200-1500 g.

Conclusions:

  • Race, sex, and transport status are vital considerations in assessing neonatal intensive care effectiveness for VLBW infants.
  • Multivariable statistical analysis aids in predicting survival probabilities for diverse VLBW infant subgroups.
  • Predicted survival probabilities can inform clinical guidelines for infants near the threshold of viability.
Abstract

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