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Relationship between salivary flow rates and Candida albicans counts
M Navazesh1, G J Wood, V J Brightman
1Department of Dental Medicine and Public Health, University of Southern California, School of Dentistry, Calif.
Summary
Whole saliva flow rates are linked to lower Candida albicans counts. This study suggests whole saliva is a better indicator of high Candida levels than parotid saliva.
Area of Science:
- Oral microbiology
- Salivary diagnostics
Background:
- Candida albicans is a common oral fungus.
- Salivary flow rate can influence oral microbial counts.
- Identifying individuals with high Candida albicans levels is important for oral health.
Purpose of the Study:
- To investigate the relationship between salivary flow rates and Candida albicans counts.
- To determine if whole saliva or parotid saliva is a better predictor of high Candida albicans levels.
Main Methods:
- Seventy-one participants provided saliva samples (unstimulated whole, chewing-stimulated whole, acid-stimulated parotid, candy-stimulated parotid) and oral rinse samples.
- Salivary flow rates and Candida albicans counts were measured.
- Statistical analyses were performed to assess correlations and differences.
Main Results:
- Unstimulated and chewing-stimulated whole saliva flow rates were negatively correlated with Candida albicans counts.
- Whole saliva flow rates differed significantly across various Candida albicans count levels.
- Stimulated parotid saliva flow rates did not show significant differences based on Candida counts.
Conclusions:
- Whole saliva flow rate is a significant predictor of Candida albicans colonization.
- Whole saliva is more effective than parotid saliva in identifying individuals with high Candida albicans counts.