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Updated: May 3, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
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A C Douds1, A E Joseph, C Finlayson

  • 1Department of Gastroenterology, St George's Hospital and Medical School, London.

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Day case liver biopsies are safe and effective for selected patients, with similar complication rates to inpatient procedures. Most patients found the day case experience acceptable, highlighting its viability.

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Area of Science:

  • Hepatology
  • Gastroenterology
  • Surgical Procedures

Background:

  • Day case liver biopsy is infrequently performed nationally.
  • It has been a routine practice for selected patients at our institution since 1989.

Purpose of the Study:

  • To audit the hospital's experience with day case liver biopsies.
  • To compare the safety and efficacy of day case versus inpatient liver biopsies.
  • To assess patient acceptability of the day case procedure.

Main Methods:

  • Retrospective audit of liver biopsies performed at a teaching hospital over 42 months.
  • Comparison of complication rates and specimen quality between day case and inpatient groups.
  • Patient acceptability assessed via questionnaire for day case biopsies.

Main Results:

  • 33% (182 of 546) of biopsies were performed as day cases.
  • Specimen quality was comparable between day case and inpatient groups.
  • Overall complication rates were similar (2.7% day case vs. 3.3% inpatient), with no deaths or hemorrhages in day cases.

Conclusions:

  • Day case liver biopsy is a safe and effective procedure for selected patients.
  • Patient satisfaction with day case liver biopsy is high (91%).
  • The practice demonstrates feasibility and patient acceptance in a routine setting.