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Louisianins A, B, C and D: non-steroidal growth inhibitors of testosterone-responsive SC 115 cells. II.
S Takamatsu1, Y P Kim, M Hayashi
1Kitasato Institute, Tokyo, Japan.
The Journal of Antibiotics
|October 1, 1995
Abstract:
New non-steroidal growth inhibitors of testosterone-responsive SC 115 cells, louisianins A (MW: 189; C11H11NO2), B (MW: 191; C11H13NO2), C (MW: 173; C11H11NO) and D (MW: 173; C11H11NO) were isolated from the cultured broth of Streptomyces sp. WK-4028. Their structures were determined on the basis of spectroscopic data. The structure of louisianin A in particular was confirmed by X-ray crystallographic analysis. The four compounds commonly possess a unique pyrindine skeleton in the molecule.