Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgical management of primary bone sarcomas

A W Yasko1, M E Johnson

  • 1Department of Surgical Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, USA.

Hematology/Oncology Clinics of North America
|August 1, 1995
PubMed
Summary

Chemotherapy has improved bone sarcoma surgery, allowing limb-saving procedures with low relapse rates. Technological advances aid skeletal reconstruction, but long-term function requires further innovation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Frozen storage is detrimental to the functionality of cream cheese and mascarpone even in high-pressure-treated samples.

Journal of dairy science·2026
Same author

Impact of moisture content and age on the properties of microwaved shelf-stable puffed snacks made from Cheddar cheese.

Journal of dairy science·2026
Same author

Use of milk powders to manufacture panela cheese by a wheyless cheesemaking process.

Journal of dairy science·2025
Same author

Impact of protein content and pH on the properties of microwaved, expanded, shelf-stable cheese puff snacks made from dairy powders.

Journal of dairy science·2025
Same author

Low-moisture part-skim mozzarella made from milk with varying casein contents.

Journal of dairy science·2025
Same author

Extending the performance shelf life of direct-salted block Gouda.

Journal of dairy science·2025

Area of Science:

  • Orthopedic Surgery
  • Surgical Oncology
  • Biomedical Engineering

Background:

  • Primary bone sarcomas necessitate complex treatment strategies.
  • Chemotherapy has significantly impacted the surgical approach to bone sarcomas.
  • Limb-salvage surgery is increasingly feasible and effective.

Purpose of the Study:

  • To evaluate the impact of chemotherapy on surgical management of primary bone sarcomas.
  • To assess the safety and efficacy of limb-salvage procedures.
  • To review technological advancements in skeletal reconstruction.
  • To discuss the long-term functional outcomes and future directions.

Main Methods:

  • Review of end-result analyses of patients undergoing surgical management for primary bone sarcomas.
  • Analysis of local tumor relapse rates in limb-salvage procedures.
  • Evaluation of technological options for skeletal reconstruction.
  • Assessment of functional outcomes post-surgery.

Main Results:

  • Limb-salvage surgery is now the standard for most patients with primary bone sarcomas.
  • Effective chemotherapy regimens have not significantly increased local tumor relapse rates.
  • Technological advancements have broadened the scope of reconstructive options.
  • Current reconstruction techniques maximize function in the short to medium term.

Conclusions:

  • Chemotherapy has revolutionized the surgical management of bone sarcomas, enabling limb preservation.
  • Skeletal reconstruction technologies have advanced significantly, improving functional outcomes.
  • Continued research is essential to ensure and improve long-term function after these complex procedures.

Related Experiment Videos