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Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis
R S Veazey1, H W Taylor, D W Horohov
1Department of Veterinary Pathology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.
Journal of Comparative Pathology
|July 1, 1995
Abstract:
The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.