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Lentigo maligna and lentigo maligna melanoma
1Pathology Services, Inc., Cambridge, MA 02139, USA.
Journal of the American Academy of Dermatology
|December 1, 1995
Summary
Lentigo maligna (LM) is a sun-induced skin lesion in older adults that can progress to lentigo maligna melanoma (LMM). Surgical removal is the preferred treatment for this melanoma in situ.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Lentigo maligna (LM) is a common pigmented lesion on sun-exposed skin in the elderly.
- It is considered a form of melanoma in situ due to its potential to evolve into lentigo maligna melanoma (LMM).
Purpose of the Study:
- To discuss the clinical, histopathologic, and epidemiologic features of LM.
- To review the prognosis and treatment options for LM.
Main Methods:
- Review of clinical presentations of LM.
- Analysis of histopathologic findings, including atypical melanocyte proliferation.
- Epidemiologic data compilation.
Main Results:
- LM presents as a slow-growing pigmented lesion on sun-damaged skin, typically head and neck.
- Histopathology shows atypical melanocytes in the epidermis and adnexa.
- Surgical excision is the primary treatment modality.
Conclusions:
- LM requires careful management due to its malignant potential.
- Early diagnosis and treatment, preferably surgical, are crucial for favorable outcomes.
- The progression risk to LMM warrants ongoing research.