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[Thorotrast kidney as a precancerous condition]
Schweizerische Medizinische Wochenschrift
|December 9, 1978
Summary
Thorotrast kidney, a condition following contrast agent use, significantly increases cancer risk. Early detection and treatment, such as surgery or regular monitoring, are crucial for managing this precancerous state.
Area of Science:
- Radiology
- Urology
- Oncology
Context:
- Retrograde pyelography with reflux can lead to thorotrast kidney.
- Thorotrast, a contrast agent, poses long-term risks.
- This study examines 9 cases of thorotrast kidney.
Purpose:
- To highlight the precancerous nature of thorotrast kidney.
- To report the high incidence of renal pelvis carcinoma following thorotrast pyelography.
- To discuss diagnostic and treatment strategies.
Summary:
- 9 cases of thorotrast kidney were analyzed.
- 6 patients developed renal pelvis carcinoma 47-31 years post-procedure.
- Radiographic findings include opaque linear densities in the calices and pyelon.
Impact:
- Thorotrast kidney is a precancerous condition with high tumor manifestation rates.
- Early ureteronephrectomy is recommended for unilateral cases.
- Regular urinary cytology aids in early malignancy detection if surgery is not feasible.