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Co-trimoxazole induced aseptic meningitis
D Pashankar1, M McArdle, A Robinson
1Duchess of York Children's Hospital, Manchester.
Archives of Disease in Childhood
|September 1, 1995
Abstract:
A 15 year old boy presented with two episodes of aseptic meningitis-like reactions after ingestion of co-trimoxazole. The diagnosis of co-trimoxazole induced aseptic meningitis was made. This syndrome should be considered in the differential diagnosis of aseptic meningitis.
Insights
Co-trimoxazole can cause drug-induced aseptic meningitis, a rare condition. This syndrome should be considered in patients presenting with meningitis symptoms after co-trimoxazole use.
Area of Science:
- Neurology
- Pharmacology
- Infectious Diseases
Background:
- Aseptic meningitis is an inflammation of the meninges not caused by bacterial infection.
- Drug-induced aseptic meningitis is a rare but serious adverse reaction to certain medications.
Observation:
- A 15-year-old male experienced two distinct episodes of aseptic meningitis-like symptoms.
- These reactions occurred shortly after the ingestion of co-trimoxazole.
Findings:
- The patient was diagnosed with co-trimoxazole-induced aseptic meningitis.
- This diagnosis was based on the temporal relationship between drug exposure and symptom recurrence.
Implications:
- Co-trimoxazole-induced aseptic meningitis should be included in the differential diagnosis for patients presenting with aseptic meningitis.
- Early recognition and discontinuation of the causative agent are crucial for patient management.