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Digoxin in clinical practice: sorting out the facts

S A Doi¹, P N Landless

¹Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.

The British Journal of Clinical Practice

|September 1, 1995

Summary

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This review clarifies current clinical practice for digoxin, covering its mechanism, efficacy, and toxicity management. It provides essential information for healthcare professionals regarding digoxin

Area of Science:

Pharmacology
Cardiology
Clinical Practice

Background:

Digoxin is a widely used cardiac glycoside with a long history.
Extensive literature exists on digoxin, necessitating a focused review for current applications.

Purpose of the Study:

To distill pertinent information on digoxin from the vast literature for contemporary clinical practice.
To provide a comprehensive overview of key aspects of digoxin therapy.

Main Methods:

Literature review focusing on seven key aspects of digoxin.
Synthesis of existing data relevant to current clinical use.

Main Results:

Detailed discussion of digoxin's mechanism of action and clinical efficacy.

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Guidance on avoiding and managing digoxin toxicity.

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Conclusions:

Digoxin remains a relevant therapeutic agent when used appropriately.
Understanding its pharmacology, efficacy, and toxicity is crucial for safe and effective patient care.