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Polymeric N-acetyl-D-glucosamine (chitin) induces prostaglandin E2 in dogs
S Minami1, Y Okamoto, A Matsuhashi
1Department of Veterinary Surgery, Faculty of Agriculture, Tottori University, Japan.
The Journal of Veterinary Medical Science
|April 1, 1995
Abstract:
The level of prostaglandin E2 (PGE2) in the exudate induced by subcutaneous implantation of a complex formed from non-woven fabric of polyester (NWF) and polymeric N-acetyl-D-glucosamine (chitin) (chitin/NWF) or by implantation of NWF in dogs was measured by radioimmunoassay. The amount of PGE2 in the exudate induced by chitin/NWF was about five times as high as that in the exudate induced by NWF (p < 0.05), while the level of PGE2 in the exudate was similar to that in serum.