[Nonspecific resistance to heterologous viral infection after immunization with smallpox vaccine]

The level of development of nonspecific resistance to influenza virus infection after immunization with variola vaccine, the dynamics of changes in DNA synthesis in the spleen cells and concentration of nonspecific immunoglobulins in the blood serum of mice after immunization and infection with influenza virus were studied. A close correlation between DNA synthesis, concentration of immunoglobulins, and the level of nonspecific resistance to heterologous virus infection was found.