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Characterization of chromosomal DNA profiles from Helicobacter pylori strains isolated from sequential gastric biopsy
1Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada.
Journal of Clinical Microbiology
|September 1, 1995
Abstract:
The restriction endonuclease profiles of DNAs from Helicobacter pylori strains isolated from 20 patients in two or more consecutive biopsy specimens over a period of up to 2 years were analyzed by pulsed-field gel electrophoresis with NotI and NruI. H. pylori strains possess a high degree of genomic diversity which was not observed to occur in vivo, and attempts to observe it in vitro were not successful.